Combined non-invasive brain stimulation (NIBS) and rehabilitation interventions have the potential to improve function in children with unilateral cerebral palsy (UCP), however their effects on developing brain function are not well understood. In a proof-of-principle study, we used single-pulse transcranial magnetic stimulation (TMS) to measure changes in corticospinal excitability and relationships to motor performance following a randomized controlled trial consisting of 10 days of combined constraint-induced movement therapy (CIMT) and cathodal transcranial direct current stimulation (tDCS) applied to the contralesional motor (...) cortex. Twenty children and young adults (mean age = 12 years, 9 months, range = 7 years, 7 months, 21 years, 7 months) with UCP participated. TMS testing was performed before, after, and 6 months after the intervention to measure motor evoked potential (MEP) amplitude and cortical silent period (CSP) duration. The association between neurophysiologic and motor outcomes and differences in excitability between hemispheres were examined. Contralesional MEP amplitude decreased as hypothesized in five of five participants receiving active tDCS immediately after and 6 months after the intervention, however no statistically significant differences between intervention groups were noted for MEP amplitude [mean difference = −323.9 μV, 95% CI = (−989, 341), p = 0.34] or CSP duration [mean difference = 3.9 ms, 95% CI = (−7.7, 15.5), p = 0.51]. Changes in corticospinal excitability were not statistically associated with improvements in hand function after the intervention. Across all participants, MEP amplitudes measured in the more-affected hand from both contralesional (mean difference = −474.5 μV) and ipsilesional hemispheres (−624.5 μV) were smaller compared to the less-affected hand. Assessing neurophysiologic changes after tDCS in children with UCP provides an understanding of long-term effects on brain excitability to help determine its potential as a therapeutic intervention. Additional investigation into the neurophysiologic effects of tDCS in larger samples of children with UCP are needed to confirm these findings. (shrink)

© 2016 Regents of the University of California.The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,062 new measurements from 721 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as supersymmetric particles, heavy bosons, axions, dark photons, etc. All the particle properties and search limits are listed in Summary Tables. We also give numerous (...) tables, figures, formulae, and reviews of topics such as Higgs Boson Physics, Supersymmetry, Grand Unified Theories, Neutrino Mixing, Dark Energy, Dark Matter, Cosmology, Particle Detectors, Colliders, Probability and Statistics. Among the 117 reviews are many that are new or heavily revised, including those on Pentaquarks and Inflation. The complete Review is published online in a journal and on the website of the Particle Data Group. The printed PDG Book contains the Summary Tables and all review articles but no longer includes the detailed tables from the Particle Listings. A Booklet with the Summary Tables and abbreviated versions of some of the review articles is also available. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

Work on the methodology of natural science involves serious difficulties over and above those encountered in any other aspect of natural science or of philosophy. Reference is to the obvious fact that in discussing methodological questions of, for example, physics, so as to be precise, it is not enough to know physics: it is also necessary to familiarize oneself with certain branches of philosophy, the history of science, and so forth. Furthermore, a professional cannot limit himself to "general familiarity" with (...) the material. He has to know the details and, if possible, the entire literature on the question under discussion. However, the volume of literature on physics has, within the memory of the author alone — that is, over approximately forty years — multiplied dozens of times. I cannot say how great has been the increase in the quantity of information on the methodology of natural science and related disciplines. But what is important is that the amount of material that has accumulated to date is enormous. Some notion of the scale of the work may be gained from the abstract journal Obshchestvennye nauki za rubezhom. Seriia 8. Naukovedenie. For example, no. 1 for 1980 contained abstracts of 72 articles and books; this amounts to over 400 titles a year . When we add to this the Soviet literature and the need to include material from many years, we arrive at a figure of four digits. Naturally, only a very small portion of the literature is made use of in any particular piece of work, but it is impossible to know beforehand which items will be specifically needed. (shrink)

Five experiments investigated how people use categories to make inductions about objects whose categorisation is uncertain. Normatively, they should consider all the categories the object might be in and use a weighted combination of information from all the categories: bet-hedging. The experiments presented people with simple, artificial categories and asked them to make an induction about a new object that was most likely in one category but possibly in another. The results showed that the majority of people focused on the (...) most likely category in making inductions, although there was a group of consistently normative responders who used information from both categories (about 25% of our college population). Across experiments the overall pattern of results suggests that performance in the task is improved not by understanding the underlying principles of bet-hedging but by increasing the likelihood that multiple categories are in working memory at the time of the induction. We discuss implications for improving everyday inductions. (shrink)

It is a strange fact that people's opinions of psychoanalysis are only rarely tentative or unemphatic. It seems that one must either love it or hate it. Professor Cioffi, in a recent paper, has shown that he is no lover of psychoanalysis, and he makes what appears to be a devastating attack on Freud's theories and methods and on the credibility of the whole psychoanalytic discipline. Without wanting to ally myself wholeheartedly with the opposite camp, I want to show that (...) many of the main contentions of his paper are wrong. I shall argue that the objections he makes which, if valid, would be the most serious for Freudian theory, are unfounded. (shrink)

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

The problem of modern principle conditions, forms and effective group cooperation interaction methods are considered. On the basis of the comparative analysis of inconsistent approaches to teambuilding, the expediency of domestic experience of collective formation use on humanistic principles of the general care is proved, that were mostly qualitative theoretically and empirically developed and checked up by long-term experience of scientific and pedagogical activity of A. S. Makarenko, I. P. Ivanov and their followers. Some little-known facts of history of their (...) approaches to formation and collective development are considered. The basic psychology-pedagogical teambuilding principles, applicable not only in pedagogical, but also in many other kinds of modern creative activity are allocated. (shrink)

The scientific career of the outstanding Russian physiologist A. A. Ukhtomskii was complex and full of contradictions. A descendant of Prince Vsevolod Big Nest [Bol'shoe Gnezdo] of Suzdal', he was strongly influenced by the traditions and legends of his caste. As a juvenile he was sent to the Nizhnii Novgorod Corps of Cadets where he developed a profound interest in philosophy, psychology, history, and literature. His fellow cadets of the same age were amazed at, and sometimes ridiculed the young Ukhtomskii's (...) attempts to find answers to the burning questions of the day in the books of Shakespeare and Dostoevsky and in scientific works. Ukhtomskii's notebooks and synopses of those years show how this youth, from age 15 to 17, pondered over cardinal problems of world view, the contradictions of Russian society, and the future of science. The barracks life of the cadets, the rigorous schedule and supervision did not suppress Ukhtomskii's persistent desire to get a closer knowledge of the life of Nizhnii Novgorod, a major mill town and river port. He managed to make the acquaintance of members of a group of Marxist workers and maintained contact with one of them, M. Ia. Iakovlev , for over 40 years. (shrink)

We consider fine hierarchies in recursion theory, descriptive set theory, logic and complexity theory. The main results state that the sets of values of different Boolean terms coincide with the levels of suitable fine hierarchies. This gives new short descriptions of these hierarchies and shows that collections of sets of values of Boolean terms are almost well ordered by inclusion. For the sake of completeness we mention also some earlier results demonstrating the usefulness of fine hierarchies.